Volume 60; Issue Suppl 2

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Gut
Volume 60; Issue Suppl 2

Gut

Volume 60; Issue Suppl 2

1

P92 CD161+ - T cells: defining their role in patients with and without chronic hepatitis C

Rajoriya, N., Willberg, C., Seigal, B., YuHoi Kang,, Phillips-Hughes, J., Collier, J., Barnes, E., Thimme, R., Klenerman, P.

Journal:

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

2

P34 No effect of tenofovir or entecavir on vitamin D levels in Chronic Hepatitis B mono-infected patients. Single centre 'real life' cohort experience

Nguyen, H.-L., Carey,, Al-Freah, M. A. B., Joe, D., Sherwood, R., Knighton, S., Harrison, P., Suddle, A., Agarwal, K.

Journal:

Year:

2011

Language:

english

File:

PDF, 113 KB

english, 2011

3

OP02 The first new monotherapy therapeutic PBC study in a decade? An international study evaluating the farnesoid X receptor agonist obeticholic acid in PBC

Jones, D., Kowdley, K., Chapman, R., Burroughs, A., Hirschfield, G., Schramm, C., Poupon, R., ParEs, A., Shapiro, D., Pruzanski, M., On behalf of,

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

4

P35 Long-term remission is achievable in autoimmune hepatitis using Tacrolimus or Mycophenolate mofetil and results in regression of fibrosis

Scott, R., White, J., Atwal, G., Taylor, N., Mortimore, G., Freeman, J., Lawson, A., Austin, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 163 KB

english, 2011

5

P40 Fast track jaundice clinic: the standard of care for hepatobiliary malignancy?

Young, K., Dundas, P., Vijayan, B., Fraser, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 83 KB

english, 2011

6

P89 Osteopontin promotes lymphocyte recruitment in steatohepatitis

Liaskou, E., Claridge, L. C., Shah, H., Oo, Y., Shaw, J., Mi, Z., Kuo, P. C., Canbay, A., Diehl, A. M., Adams, D. H., Syn, W.-K.

Journal:

Year:

2011

Language:

english

File:

PDF, 104 KB

english, 2011

7

P09 Validation of a novel biomarker model for the prediction of non-alcoholic steatohepatitis in patients with non-alcoholic fatty liver disease

Tanwar, S., Trembling, P., Guha, I. N., Parkes, J., Kaye, P., Burt, A. D., Ryder, S. D., Aithal, G. P., Day, C. P., Rosenberg, W. M.

Journal:

Year:

2011

Language:

english

File:

PDF, 85 KB

english, 2011

8

P93 NF B activation by TLR agonists is deficient in macrophages lacking STAT2

Alazawi, W., Gamero, A., Heath, H., Smith, P., Jacobs, M., Waters, J., Foster, G. R.

Journal:

Year:

2011

Language:

english

File:

PDF, 62 KB

english, 2011

9

P70 Telaprevir in combination with peginterferon and ribavirin in genotype 1 HCV Treatment-Naive patients: final results of phase 3 ADVANCE Study

Dusheiko, G. M., Bengtsson, L., Adda, N., Kauffman, R., Jacobson, I. M.

Journal:

Year:

2011

Language:

english

File:

PDF, 79 KB

english, 2011

10

OP03 Telaprevir-based therapy in G1 HCV-infected patients with prior null response, partial response or relapse to peginterferon/ribavirin: REALIZE trial final results

Foster, G., Zeuzem, S., Andreone, P., Pol, S., Lawitz, E., Diago, M., Roberts, S., Focaccia, R., Younossi, Z., A H,, Heeswijk, R. V., de Meyer, S., Luo, D., Picchio, G., Beumont, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 130 KB

english, 2011

11

P08 Spontaneous bacterial peritonitis prophylaxis: reducing the incidence of c difficile infection

Jafferbhoy, H., Miller, M. H., Shekar, C., Lockhart, M., Dillon, J. F.

Journal:

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

12

P73 Preliminary results of the Study of Acute Liver Transplant (SALT): NSAID exposure and risk of acute liver failure leading to transplantation in 7 European countries

Thorburn, D., Gulmez, E., Lignot, S., Larrey, D., de Vries, C., Perez-Gutthann, S., Montastruc, J. L., Sturkenboom, M., Benichou, J., Velo, G., Caputi, A., Salvo, F., Hamoud, F., Micon, S., Lassalle,

Journal:

Year:

2011

Language:

english

File:

PDF, 56 KB

english, 2011

13

P20 First report of the long-term efficacy of a novel endoscopic radiofrequency ablation technique for malignant biliary obstruction

Kallis, Y., Phillips, N., Steel, A., Baldwin, C., Nicholls, J., Jiao, L., Vlavianos, P., Habib, N., Westaby, D.

Journal:

Year:

2011

Language:

english

File:

PDF, 70 KB

english, 2011

14

P12 Measuring the effectiveness of a multidisciplinary NASH Clinic

Peake, C. M., Cobbold, J. F. L., Anstee, Q. M., Yee, M., Thursz, M. R.

Journal:

Year:

2011

Language:

english

File:

PDF, 110 KB

english, 2011

15

P13 The performance validity of breath sample analysis in the diagnosis of hepatic encephalopathy in patients with cirrhosis

Halliday, E., Stevens, S., Stubbs, M., Morris, R., Morgan, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 124 KB

english, 2011

16

P14 Phenotypic and functional profile of CD4posCD25high regulatory T cells in autoimmune hepatitis/systemic lupus erythematosus overlap syndrome

Longhi, M. S., Ma, Y., Samyn, M., Gordon, P., Mieli-Vergani, G., Vergani, D.

Journal:

Year:

2011

Language:

english

File:

PDF, 62 KB

english, 2011

17

P15 Multiple defects of the immunoregulatory system contribute to the development of autoimmune hepatitis

Wang, P., Longhi, M. S., Mieli-Vergani, G., Vergani, D., Ma, Y.

Journal:

Year:

2011

Language:

english

File:

PDF, 62 KB

english, 2011

18

P02 Apoptosis in paracetamol-induced acute liver failure: importance of extra-hepatic organ dysfunction

Possamai, L. A., Quaglia, A., Antoniades, C. G., Zingarelli, V., McPhail, M. J., Auzinger, G., Bernal, W., Heaton, N. D., Hughes, R., Ma, Y., Thursz, M., Wendon, J. A., Mitry, R. R.

Journal:

Year:

2011

Language:

english

File:

PDF, 205 KB

english, 2011

19

P23 Comparison of enhanced liver fibrosis test and transient elastography for the non-invasive assessment of liver fibrosis in chronic hepatitis B

Trembling, P. M., Lampertico, P., Parkes, J., Tanwar, S., Viganu, M., Facchetti, F., Colombo, M., Rosenberg, W. M.

Journal:

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

20

P27 Reduction in alanine aminotransferase values in diabetic patients receiving long-term oral antibiotics: does modulation of gut flora affect hepatic inflammation in non-alcoholic fatty liver disease?

Leach, L., Cobbold, J. F. L., Valabhji, J., Thursz, M. R.

Journal:

Year:

2011

Language:

english

File:

PDF, 61 KB

english, 2011

21

P29 Reduced expression of Tim-3 renders Th1 and Th17 effector cells less amenable to T-reg control in autoimmune hepatitis

Liberal, R., Mieli-Vergani, G., Vergani, D., Longhi, M. S.

Journal:

Year:

2011

Language:

english

File:

PDF, 72 KB

english, 2011

22

P30 Lung injury and its prognostic significance in acute liver failure

Audimoolam, V. K., McPhail, M., Desai, S., Willars, C., Bernal, W., Wendon, J. A., Auzinger, G.

Journal:

Year:

2011

Language:

english

File:

PDF, 58 KB

english, 2011

23

P31 Predictors of fluid responsiveness in patients with acute liver failure

Audimoolam, V. K., Mcphail, M., Willars, C., Bernal, W., Wendon, J. A., Auzinger, G.

Journal:

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

24

P33 Serum total cortisol and plasma free cortisol response after low dose short synacthen test in stable cirrhosis

Fede, G., Spadaro, L., Tomaselli, T., Privitera, G., Scicali, R., Vasianopoulou, P., Martin, N., Thomas, M., Purrello, F., Burroughs, A. K.

Journal:

Year:

2011

Language:

english

File:

PDF, 59 KB

english, 2011

25

P04 A dose effect of the disease risk gene HLA DR3 contributes to numerical and functional impairment of CD4+CD25+ regulatory T cells in patients with autoimmune hepatitis

Wang, P., Underhill, J., Longhi, M. S., Mieli-Vergani, G., Ma, Y., Vergani, D.

Journal:

Year:

2011

Language:

english

File:

PDF, 109 KB

english, 2011

26

P45 Natural killer cell cytotoxicity is enhanced in injection drug users with apparent resistance to hepatitis C virus infection

Warshow, U., Sieberhagen, C., Hegazy, D., Kaminski, E., Knapp, S., Khakoo, S., Cramp, M. E.

Journal:

Year:

2011

Language:

english

File:

PDF, 78 KB

english, 2011

27

P48 Telaprevir substantially improved SVR rates across all IL28B genotypes in the advance trial

Dusheiko, G. M., Jacobson, I. M., Catlett, I., George, S., Seepersaud, S., Ramachandran, R., Sussky, K., Kauffman, R. S., Botfield, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

28

P07 Socio-demographic and behavioural determinants of abnormal liver function in a multi ethnic population in the UK: the LOLIPOP study

Fraser, S. D. S., Parkes, J., Roderick, P. J., Kooner, J. S., Chambers, J.

Journal:

Year:

2011

Language:

english

File:

PDF, 73 KB

english, 2011

29

P52 Macrophage inflammatory protein-1 /CC chemokine ligand 3 and tumour-associated macrophages in hepatitis C virus-related hepatocellular carcinoma: relation to tumour progression and angiogenesis

El Aggan, H., Helmy, M., El Deeb, N., Zeid, A., Fawzy, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 74 KB

english, 2011

30

OP15 Discovery of new liver fibrosis markers in hepatitis C patients using proteomics

Gangadharan, B., Bapat, M., Rossa, J., Antrobus, R., Chittenden, D., Kampa, B., Barnes, E., Dwek, R. A., Zitzmann, N.

Journal:

Year:

2011

Language:

english

File:

PDF, 61 KB

english, 2011

31

P56 What is the best method of case finding for chronic viral hepatitis in migrant communities?

Lewis, H., Burke, K., Begum, S., Ushiro-Limb, I., Foster, G.

Journal:

Year:

2011

Language:

english

File:

PDF, 59 KB

english, 2011

32

P16 Non-invasive evaluation of fibrosis in paediatric chronic liver disease

Fitzpatrick, E., Basso, M.-S., Quaglia, A., Mitry, R. R., Dhawan, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 58 KB

english, 2011

33

P53 The cost-effectiveness of HCV antiviral treatment for injecting drug user populations

Martin, N. K., Vickerman, P., Foster, G. R., Miners, A., Hutchinson, S. J., Goldberg, D. J., Hickman, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 61 KB

english, 2011

34

P88 Vascular adhesion protein-1 (VAP-1) modulates glucose and lipid uptake in Non-Alcoholic Fatty Liver Disease (NAFLD)

Karim, S., Liaskou, E., Youster, J., Lim, F.-L., MacAulay, K., Jalkanen, S., Adams, D. H., Lalor, P. F.

Journal:

Year:

2011

Language:

english

File:

PDF, 117 KB

english, 2011

35

OP08 NAFLD related HCC is rising dramatically in the North of England

Reeves, H. L., Graham, J., Aslam, T., Chattopadyhay, D., Das, D., Patanwala, I., Rose, J., Jaques, B., Manas, D., Hudson, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 61 KB

english, 2011

36

P01 The effect of intraoperative N-acetylcysteine on hepatocellular injury during laparoscopic bariatric surgery: a randomised controlled trial

Belgaumkar, A. P., Carswell, K. A., Mitry, R. R., Hughes, R. D., Dhawan, A., Patel, A. G.

Journal:

Year:

2011

Language:

english

File:

PDF, 152 KB

english, 2011

37

P10 Whole-exome-Sequencing-based discovery of novel syndromic form of neonatal cholestasis

Hartley, J. L., Simpson, M., Tee, L., Brown, R. M., Kirkham, S., Pasha, S., Trembath, R. C., Gissen, P., Maher, E. R., Kelly, D. A., Morgan, N. V.

Journal:

Year:

2011

Language:

english

File:

PDF, 61 KB

english, 2011

38

P100 Liver transplantation (LT) results in reduced recipient Natural Killer (NK) cell activation with associated down regulation of activating receptors NKp30 and NKp46 but not NKG2D

Jamil, K. M., Cheent, K. S., Agarwal, K., Alexander, G. J., Heneghan, M. A., Khakoo, S. I.

Journal:

Year:

2011

Language:

english

File:

PDF, 120 KB

english, 2011

39

P57 The IL28B gene SNP rs12979860 CC haplotype, predictor of response to treatment in chronic HCV infection, is associated to high numbers of CD56bright NK cells, low numbers of CD3-CD56-CD16+ NK cells and low HCV-specific IL-10 production

Carey, I., Bruce, M., Mendes, A., Scalori, A., Joshi, D., Agarwal, K., Mieli-Vergani, G., Vergani, D.

Journal:

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

40

P61 Bone mineral density loss in tenofovir treated Chronic Hepatitis B Virus (HBV) patients is a consequence of Vitamin D deficiency and not Tenofovir therapy

Gill, U. S., Al-shamma, S., Burke, K., Ross, V., Marley, R. T. C., Kooner, P., Foster, G. R., Kennedy, P. T. F.

Journal:

Year:

2011

Language:

english

File:

PDF, 49 KB

english, 2011

41

P64 Central nervous system involvement in patients with chronic hepatitis C virus infection and minimal liver disease

Williams, E., Heeren, M., Jackson, C. D., Pflugrad, H., Krause, J., Weber, L. M., Wiessenborn, K., Morgan, M. Y.

Journal:

Year:

2011

Language:

english

File:

PDF, 62 KB

english, 2011

42

P69 How to re-engage patients with Hepatitis C infection: linking to Methadone prescribing works

Burnett, S., Dundas, P., McLernon, D. J., Fraser, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 54 KB

english, 2011

43

P71 A model to improve performance of current category 9 UK listing criteria: early liver graft dysfunction. A single centre cohort

Al-Freah, M. A. B., Dionigi, E., McPhail, M. J. W., Foxton, M., Auzinger, G., Rela, M., Heaton, N. D., O'Grady, J. G., Heneghan, M. A., Bernal, W., Wendon, J. A.

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

44

P74 Hepatocyte transplantation in rats with acute liver failure using cells labelled with a clinical grade MRI contrast agent

Puppi, J., Hughes, R. D., Modo, M., Mitry, R. R., Dhawan, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 53 KB

english, 2011

45

P87 Vascular Adhesion Protein-1 promotes increases in liver infiltrating CD4+ T cells and NKT cells and induction of fibrogenesis in steatohepatitis

Claridge, L. C., Weston, C. J., Haughton, E. L., Westerlund, N., Reynolds, G. M., Lalor, P. F., Tomlinson, J. W., Smith, D. J., Day, C. P., Adams, D. H.

Journal:

Year:

2011

Language:

english

File:

PDF, 50 KB

english, 2011

46

P90 -1 antitrypsin (a1AT) polymers cause extreme hepatocyte ageing

Mela, M., Davies, S., Verma, S., Tachtatzis, P., Miranda, E., Lomas, D. A., Coleman, N., Alexander, G.

Journal:

Year:

2011

Language:

english

File:

PDF, 142 KB

english, 2011

47

OP06 Maternal obesity programs offspring innate immune dysregulation in non-alcoholic fatty liver disease

Mouralidarane, A., Soeda, J., Samuelsson, A.-M., Taylor, P., Poston, L., Oben, J. A.

Journal:

Year:

2011

Language:

english

File:

PDF, 68 KB

english, 2011

48

P102 CLEVER-1 mediates the transmigration of B cells across human hepatic sinusoidal endothelium

Shetty, S., Weston, C., Oo, Y., Stamataki, Z., Salmi, M., Jalkanen, S., Lalor, P., Adams, D.

Journal:

Year:

2011

Language:

english

File:

PDF, 96 KB

english, 2011

49

P103 Metabolic profiling of the rat liver after chronic ingestion of -naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy

Solanky, B. S., Sanchez-Canon, G. J., Cobbold, J. F. L., Taylor-Robinson, S. D., Bell, J. D., Scudamore, C. L., Holder, J. C., So, P.-W., Cox, I. J.

Journal:

Year:

2011

Language:

english

File:

PDF, 49 KB

english, 2011

50

P18 Liver fibrosis assessed by transient elastography predicts response in chronic hepatitis C infected patients treated with PEG-Interferon and Ribavirin

Nkhoma, A. N. S., Sheridan, D. A., Price, D. A., Schmid, M. L., Miller, C., Baxter, K., Bassendine, M. F., McPherson, S.

Journal:

Year:

2011

Language:

english

File:

PDF, 67 KB

english, 2011

51

P24 Presence of impaired baroreceptor sensitivity is a poor prognostic marker in cirrhosis

Rye, K., Mortimore, G., Austin, A., Freeman, J.

Journal:

Year:

2011

Language:

english

File:

PDF, 54 KB

english, 2011

52

P25 Fragility fracture risk in cirrhosis: a comparison of the fracture risk assessment tool (FRAX_), BSG and NICE guidelines

Ayres, L., Digby-Bell, J., Clarke, S., Dhanda, A., Caddick, K., Collins, P.

Journal:

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

53

P28 Defective T-regulatory function in autoimmune hepatitis may partially derive from a pro-inflammatory skewing of Gal9+T-regs

Liberal, R., Mieli-Vergani, G., Vergani, D., Longhi, M. S.

Journal:

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

54

P38 Homodynamic effects of prolonged treatment with midodrine in non-azotemic pre-ascitic, ascitic and refractory ascites cirrhotic patients

Badran, H., Moaty, A., Basuni, A. A., Aziz, W. F. A., Rewisha, E. A., Waked, I. A.

Journal:

Year:

2011

Language:

english

File:

PDF, 54 KB

english, 2011

55

P39 An analysis of rebleeding rates for variceal haemorrhage at a regional centre: what is the applicability and potential cost for early TIPS?

Harman, D., McCorry, R., Khan, F., O'Neill, R., James, M., Ryder, S., Aithal, G., Guha, I. N.

Journal:

Year:

2011

Language:

english

File:

PDF, 87 KB

english, 2011

56

P41 Liver disease-specific gene expression profile in hepatocellular carcinoma

Journal:

Year:

2011

Language:

english

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PDF, 150 KB

english, 2011

57

P42 Role of Acoustic Radiation Force Impulse (ARFI) elastography in the non-invasive assessment of liver fibrosis in chronic viral hepatitis: a simultaneous comparison with liver histology in a secondary care setting

Kandiah, K., Sangwaiya, M. J., Tadrous, P., Shorvon, P., Sherman, D.

Journal:

Year:

2011

Language:

english

File:

PDF, 116 KB

english, 2011

58

P46 The prediction of liver related outcomes using histological tools as an endpoint for studies evaluating anti-fibrotic therapies

Dolman, G. E., Li, G., Burgess, G., Gray, T., Zaitoun, A. M., Irving, W., Guha, I. N.

Journal:

Year:

2011

Language:

english

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PDF, 56 KB

english, 2011

59

P47 De-novo antiviral therapy with nucleos(t)ide analogues in 'real-life' patients with chronic hepatitis B infection: comparison of virological responses between lamivudine + adefovir vs entecavir vs tenofovir therapy

Carey, I., Nguyen DorothyJoe, H., Al-Freah, M., Knighton, S., Bruce, M., Suddle, A., Harrison, P. M., Agarwal, K.

Journal:

Year:

2011

Language:

english

File:

PDF, 67 KB

english, 2011

60

P50 Apolipoprotein E and low-density, apolipoprotein B associated lipoviral particles in chronic hepatitis C infection: evidence for genotype-specific modulation of lipid pathways

Bridge, S., Sheridan, D., Felmlee, D., Crossey, M., Thomas, H., Taylor-Robinson, S., Toms, G., Neely, D., Bassendine, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

61

P54 CHASE-B (Chinese Hepatitis Awareness, Surveillance and Education): a pilot of targeted case finding for hepatitis B virus (HBV) in the British-Chinese community

McPherson, S., Valappil, M., Moses, S., Eltringham, G., Miller, C., Baxter, K., Brown, B., Clapper, P., Chan, A., Hudson, M., Bassendine, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

62

P55 HCV quasispecies analysis of patients with genotype 3 HCV who relapse suggest two different mechanisms of relapse

Waters, J., Shoeb, D., Foster, G. R.

Journal:

Year:

2011

Language:

english

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PDF, 49 KB

english, 2011

63

P06 Role of serum hyaluronic acid in predicting mortality in patients with chronic liver disease

Plevris, N., Mcavoy, N. C., Hayes, P. C.

Journal:

Year:

2011

Language:

english

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PDF, 76 KB

english, 2011

64

P60 Pre-treatment IP-10 concentrations are associated with a sustained virological response in HIV/HCV co-infected patients

Joshi, D., Bruce, M., Suddle, A., Taylor, C., Carey, I., Agarwal, K.

Journal:

Year:

2011

Language:

english

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PDF, 49 KB

english, 2011

65

P65 Oral anti-viral therapy shaping the indications for hepatitis B liver transplantation over 2 decades

Oo, Y. H., Gunson, B., Mutimer, D. J.

Journal:

Year:

2011

Language:

english

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PDF, 62 KB

english, 2011

66

P66 Low pre-treatment plasma HBsAg level and its decline during add-on interferon treatment predict response to combined lamivudine/interferon therapy in tolerant children with infancy-acquired chronic hepatitis B

Carey, I., Horner, M., Bruce, M., Bansal, S., Vergani, D., Mieli-Vergani, G.

Journal:

Year:

2011

Language:

english

File:

PDF, 76 KB

english, 2011

67

P67 Switch to other nucleos(t)ide analogues therapy in chronic hepatitis B cohort on long-term de-novo combination therapy with lamivudine plus adefovir: efficacy and safety

Carey, I., Mendes, A., Joshi, D., Bruce, M., Knighton, S., Scalori, A., Hughes, S., Al-Freah, M., Suddle, A., Harrison, P. M., Agarwal, K.

Journal:

Year:

2011

Language:

english

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PDF, 51 KB

english, 2011

68

P75 Impaired cardiorespiratory reserve in primary biliary cirrhosis patients undergoing liver transplant assessment

Prentis, J., Jones, D. E., Trenell, M. I., Snowden, C. P.

Journal:

Year:

2011

Language:

english

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PDF, 69 KB

english, 2011

69

P77 A Pharmacist delivered stratified conversion protocol from Hepatitis B Immunoglobulin (HBIG) to tenofovir or entecavir is efficacious, safe and cost-effective for prevention of recurrence of Hepatitis B virus (HBV) in Liver Transplant (LT) recipients

Knighton, S., Agarwal, K., Heneghan, M., O'Grady, J., Bruce, M., Carey, I., Heaton, N., Suddle, A.

Journal:

Year:

2011

Language:

english

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70

P81 Pre-transplant histological assessment in patients with alcoholic liver disease does not predict risk of recidivism post liver transplantation

Prentis, J., McPherson, S., Burt, A., Manas, D., Snowden, C., Hudson, M., Masson, S.

Journal:

Year:

2011

Language:

english

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71

P82 Haemoglobin level prior to liver transplantation: does it predict the outcome?

Kamperidis, N., Al-Freah, M. A. B., Heneghan, M. A., Heaton, N., Goodhand, J. R., O'Grady, J.

Journal:

Year:

2011

Language:

english

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PDF, 77 KB

english, 2011

72

P84 Towards cell based therapy for 1-antitrypsin deficiency through targeted bi-allelic gene correction in human iPS cells

Rashid, S. T., Yusa, K., Strick-Marchand, H., Rouhani, F. J., Marciniak, S. J., Miranda, E., Ordonez, A., Hannan, N., Alexander, G., di-Santo, J., Bradley, A., Lomas, D. A., Vallier, L.

Journal:

Year:

2011

Language:

english

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73

P85 Human mesenchymal stem cells bind preferentially to injured liver in a 1-integrin and CD44 dependent manner

Aldridge, V., Davies, N., Youster, J., Kavanagh, D., Kalia, N., Lalor, P., Frampton, J., Newsome, P.

Journal:

Year:

2011

Language:

english

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PDF, 66 KB

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74

P94 Rapamycin helps maintain the regulatory phenotype of cytochrome P450IID6-specific Treg expanded from patients with autoimmune hepatitis type 2 by reducing the number of IFN + cells

Holder, B., Grant, C. R., Ma, Y., Mieli-Vergani, G., Vergani, D., Longhi, M. S.

Journal:

Year:

2011

Language:

english

File:

PDF, 125 KB

english, 2011

75

P97 Lymphocyte-hepatocyte interactions: hepatitis C virus changes the rules

Stamataki, Z., Qureshi, O. S., Reynolds, G. M., Hibbert, L., Waters, J., Foster, G. R., Rappoport, J. Z., Hubscher, S. G., Adams, D. H., McKeating, J. A.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

76

P98 The effects of Th17 cytokines on liver parenchymal cells shape the microenvironment for local generation of Th17/Tc17 in inflammatory liver disease

Humphreys, E. H., Muirhead, G. M., Bhogal, R. H., Eksteen, B., Afford, S. C., Oo, Y. H., Adams, D. H.

Journal:

Year:

2011

Language:

english

File:

PDF, 97 KB

english, 2011

77

OP01 Who dies from alcoholic liver disease and where are possible therapeutic interventions missed? An analysis of 755 deaths in a health community 2007-2010

Ryder, S., Coles, T., Bash, K., Allen, T.

Journal:

Year:

2011

Language:

english

File:

PDF, 55 KB

english, 2011

78

OP11 Are simple non-invasive scoring systems for fibrosis reliable in patients with NAFLD and normal ALT levels?

McPherson, S., Anstee, Q., Henderson, E., Burt, A., Day, C.

Journal:

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

79

OP12 Similar Svr Rates In Il28b Cc, Ct Or Tt prior relapser, partial- or null-responder patients treated with telaprevir/peginterferon/ribavirin: retrospective analysis of the Realize Study

Foster, G. R., Pol, S., Aerssens, J., Zeuzem, S., Andreone, P., Lawitz, E. J., Roberts, S., Younossi, Z., Focaccia, R., Horban, A., Pockros, P. J., Van Heeswijk, R., de Meyer, S., Luo, D., Beumont, M.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

80

OP14 Identification and characterisation of a Novel Ly-6Cintermediate intrahepatic macrophage population which mediates the resolution of liver fibrosis, is induced by phagocytosis and can be manipulated therapeutically in vivo

Ramachandran, P., Pellicoro, A., Vernon, M. A., Boulter, L., Aucott, R. L., Forbes, S. J., Iredale, J. P.

Journal:

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

81

OP07 Phenotypic description of a large cohort of PSC patients in the UK

Srivastava, B., Muriithi, A., Brown, M., Alexander, G., Karlsen, T. H., Rushbrook, S., Chapman, R. W.

Journal:

Year:

2011

Language:

english

File:

PDF, 52 KB

english, 2011

82

P101 Regulatory T cells exhibit reduced phenotypic stability upon pro-inflammatory challenge in autoimmune hepatitis

Grant, C. R., Holder, B., Ma, Y., Mieli-Vergani, G., Vergani, D., Longhi, M. S.

Journal:

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

83

P19 Symptomatic Epstein Barr Virus (EBV) Hepatitis is uncommon, but occurs in patients of any age, including the elderly

Vine, L., Shephard, K., Grimes, D., Bendall, R., Dalton, H.

Journal:

Year:

2011

Language:

english

File:

PDF, 56 KB

english, 2011

84

P03 The diagnostic value of transient elastography compared to clinical acumen, laboratory tests and ultrasound? Is there added value?

Dolman, G. E., Ferguson, A., Harris, S., Zaitoun, A. M., James, M., Ryder, S. D., Aithal, G. P., Guha, I. N.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

85

P32 Liver mobilisation during liver resection induces immediate and profound hepatocellular damage and inflammation in humans

van den Broek, M. A. J., Shiri-Sverdlov, R., Schreurs, J. J. W., Bloemen, J. G., Bieghs, V., Buurman, W. A., Dejong, C. H. C., Olde Damink, S. W. M.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

86

P37 Platelet count and spleen size: avoidance of screening endoscopy for varices in patients with hepatitis C cirrhosis

Gerada, J., Gerada, E., Sen, S., Griffiths, W. J.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

87

P49 Treating hepatitis C in the patient's home: a hospital and homecare partnership

Jack, K., Barnett, J., Thomson, B.

Journal:

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

88

P05 Combination of serum biomarkers for the diagnosis of hepatocellular carcinoma

Johnson, P., Teng, M., Pirrie, S., Palmer, D., Berhane, S., Stocken, D.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

89

P58 Genetic, virological and immunological pre-treatment predictors of therapy response to Peg-IFN/ribavirin in children with chronic hepatitis C

Carey, I., Bruce, M., Bansal, S., Tizzard, S., Joshi, D., Vergani, D., Mieli-Vergani, G.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

90

P62 Immunological analysis and clinical profile of Chronic Hepatitis B Virus (HBV) infection in the younger patient

Kennedy, P. T. F., Sandalova, E., Jo, J., Gill, U. S., Li, L., Ushiro-Lumb, I., Naik, S., Foster, G. R., Bertoletti, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 93 KB

english, 2011

91

P76 Meta-analysis of published evidence supports use of King's College criteria over model for end stage liver disease in outcome prediction in acute liver failure

McPhail, M. J. W., Senvar, N., Wendon, J. A., Bernal, W.

Journal:

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

92

P78 Long-term antibiotic prescription in patients relisted for late hepatic artery thrombosis is associated with greater waiting list mortality independent of meld

Smith, M., Leithead, J., Materacki, L., Sagar, V., Gunson, B., Bramhall, S., Mutimer, D., Shah, T.

Journal:

Year:

2011

Language:

english

File:

PDF, 54 KB

english, 2011

93

P96 Serum protein N-glycosylation as a biomarker of paediatric NAFLD

Fitzpatrick, E., Blomme, B., Quaglia, A., Bruyne, R. D., Vlierberghe, H. V., Dhawan, A.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

94

OP13 CD8b low T cells are a prominent, functionally distinct population in chronic hepatitis B infection

Marrinan, E., Walker, L., Barnes, E., Klenerman, P.

Journal:

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

95

OP09 TIPS outcomes for refractory ascites: a single centre experience

Macnaughtan, J., Hogan, B., Tritto, G., Mullan, M., Yu, D., Thorburn, D., O'Beirne, J., Jalan, R., Patch, D., Burroughs, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

96

P104 Coagulation proteins in liver fibrosis: a role for tissue factor and fibrin/fibrinogen

Dhar, A., Kampscheur, M., Sadiq, F., Levene, A., Ladva, S., Poskitt, B., Goldin, R., Thursz, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 49 KB

english, 2011

97

P105 Biliary drainage in a rat: a long-term continuous drainage model resulting in liver damage and an altered FXR pathway, lipid and cholesterol metabolism

Koelfat, K. V. K., Visschers, R. G. J., Hodin, C. M., Shiri-Sverdlov, R., Buurman, W. A., Lenaerts, K., Damink, S. W. M. O.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

98

P11 Induction of hyperammonaemia from the small and large intestine in patients with cirrhosis with magnetic resonance quantification of brain water and metabolites

Mardini, H., Smith, F., Blamirel, A., Record, C.

Journal:

Year:

2011

Language:

english

File:

PDF, 113 KB

english, 2011

99

P21 Actively injecting drug users can be successfully treated with antiviral therapy for HCV, are unlikely to be re-infected, and significantly reduce their illicit drug use

Lewis, H., Ibrahim, N., Mirza, M., Hothi, J., Wilkinson, M., Foster, G.

Journal:

Year:

2011

Language:

english

File:

PDF, 67 KB

english, 2011

100

P26 Rapid identification, triage and management of alcohol related hospital admissions

Aspinall, R. J., Atkins, S., Rackham, K., Barratt, T., Schmidt, P., Ward, J., Bowman, D.

Journal:

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

101

P43 Cellular protein cyclophilin A is involved in hepatitis B virus replication and its inhibition with DEB025 (alisporivir) or NIM811 demonstrates antiviral activity in vitro

Chokshi, S., Phillips, S., Riva, A., Naoumov, N.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

102

P51 Interferon-induced fatigue in hepatitis C infected patients is associated with increased expression of indoleamine 2,3-dioxygenase in peripheral blood mononuclear cells

Gess, M., Forton, D., Myint, A. M.

Journal:

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

103

P59 Subanalyses of the Telaprevir lead-in arm in the realize study: response at week 4 is not a substitute for prior null response categorisation

Journal:

Year:

2011

Language:

english

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english, 2011

104

P63 Ribavirin uptake by primary human hepatocytes corresponds to equilibrative nucleoside transporter 1 expression

Baloch, B. K., Chen, L., Ilyas, M., Irving, W., Thomson, B. J.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

105

P80 Patient characteristics and outcomes in a 'Hub and Spoke Model' for liver transplantation provision: The South West Liver Unit/King's College Experience

Petrova, M., Fung, M., Cramp, M. E., Mitchell, J. D., Cross, T. J. S.

Journal:

Year:

2011

Language:

english

File:

PDF, 81 KB

english, 2011

106

P86 5 -reductase-1 knockout promotes steatosis but protects against hepatocarcinogenesis in a murine model of NAFLD

Dowman, J. K., Hopkins, L. J., Armstrong, M. J., Gathercole, L., Shaw, J., Hubscher, S. G., Tomlinson, J. W., Newsome, P. N.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

107

P91 Dual mechanism of NK cell inhibition by the HCV core 35-44 peptide

Cheent, K. S., Khakoo, S. I.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

108

P99 FXR stimulation with INT-747 in a rat biliary drainage model protects from hepatocellular injury after loss of enterohepatic circulation

Visschers, R. G. J., Koelfat, K. V. K., Hodin, C. M., Shiri-Sverdlov, R., Buurman, W. A., Mookerjee, R., Lenaerts, K., Damink, S. W. M. O.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

109

OP05 The impact of comorbidities on outcome of patients assessed for liver transplantation, waiting list mortality and post liver transplantation survival using the Charlson comorbidity index

Al-Freah, M. A. B., Dionigi, E., Blackmore, L., Johnston, E., Zubir, A., Foxton, M., Bernal, W., Auzinger, G., Rela, M., Heaton, N. D., O'Grady, J. G., Heneghan, M. A., Wendon, J. A.

Journal:

Year:

2011

Language:

english

File:

PDF, 55 KB

english, 2011

110

P17 TIPS outcomes for Budd-Chiari: a single tertiary centre experience

Macnaughtan, J., Hogan, B., Tritto, G., Mullan, M., Yu, D., Thorburn, D., O'Beirne, J., Jalan, R., Patch, D., Burroughs, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

111

P22 Gall bladder length on ultrsonography as a screening tool in identification of auto immune sclerosing cholangitis

McKiernan, P., Batra, A., Au-Yong, K., Kelly, D. A., Alton, H.

Journal:

Year:

2011

Language:

english

File:

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english, 2011

112

P36 Morbidity and mortality associated with varices in patients with primary biliary cirrhosis

Patanwala, I. M., Walter, R., Newton, J., Hudson, M., Jones, D. E.

Journal:

Year:

2011

Language:

english

File:

PDF, 117 KB

english, 2011

113

P44 Use of Intralipid infusion to analyse apolipoprotein B (apoB) and HCV RNA kinetics in chronic infection

Felmlee, D., Sheridan, D., Bridge, S., Packard, C., Caslake, M., Toms, G., Neely, D., Bassendine, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 49 KB

english, 2011

114

P68 Is it worth testing unstable drug users for hepatitis C?

Stephens, B. P.

Journal:

Year:

2011

Language:

english

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PDF, 68 KB

english, 2011

115

P72 Liver transplantation for familial amyloidosis; long-term data from the Familial Amyloid Polyneuropathy World Transplant Registry (FAPWTR)

Stangou, A., Wilczek, H., Larsson, M., Suhr, O., Bo-G Ericzon,

Journal:

Year:

2011

Language:

english

File:

PDF, 79 KB

english, 2011

116

P79 Plasma succinylacetone is raised after liver transplantation for tyrosinaemia type 1 and is associated with reduced porphobilinogen synthase activity suggesting it is functional

Bartlett, D. C., Preece, M. A., Holme, E., Lloyd, C., Newsome, P. N., McKiernan, P. J.

Journal:

Year:

2011

Language:

english

File:

PDF, 96 KB

english, 2011

117

P83 Combined liver and kidney transplantation: a single centre experience

Smith, M., Rye, K., Haldane, T., Gunson, B., Bramhall, S., Mutimer, D.

Journal:

Year:

2011

Language:

english

File:

PDF, 77 KB

english, 2011

118

OP04 Synergistic influence of tapasin and HLA class I protection against chronic Hepatitis C virus infection

Ashraf, S., Knapp, S., Becford-Tackoir, C., Brooks, C., Little, A.-M., Alexander, G., Cramp, M., Khakoo, S. I.

Journal:

Year:

2011

Language:

english

File:

PDF, 128 KB

english, 2011

119

OP10 End-stage methotrexate-associated chronic liver disease in the USA: interaction of drug, host and environmental factors

Dawwas, M. F., Aithal, G. P.

Journal:

Year:

2011

File:

PDF, 46 KB

2011